Pholcodine solubility in water
WebTwo quaternary amine derivatives of pholcodine (3-(β-morpholinylethyl)-N-methyl morphinium iodide) and 3-(β-N-methyl-morpholinium-ethyl) morphine iodide) were … WebJul 15, 2013 · Pholcodine monohydrate (7,8-didehydro-4,5α-epoxy-17-methyl-3-[2 (morpholin-4-yl)ethoxy]morphinan-6α-ol monohydrate) (Fig. 1) is a semisynthetic morphine derivative extensively used worldwide as antitussive active pharmaceutical ingredient (API) [1], [2], [3].The substance is considered generally safer for medical application compared …
Pholcodine solubility in water
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WebChemical and physical properties of Pholcodine. Advanced search Similarity search. Chemical Properties of Pholcodine (CAS 509-67-1) InChI ... Log10 of Water solubility in mol/l. logP oct/wat: Octanol/Water partition coefficient. McVol : McGowan's characteristic volume (ml/mol). WebSep 27, 2006 · Four hundred milligrams of pholcodine were dissolved in 35 ml of water, and then the pH of the solution was adjusted to 7.4 with 0.1 M HCl. This solution was …
WebFrom a chemical point of view, pholcodine and NMBAs are believed to share the same IgE-binding epitope, which contains the quaternary ammonium ion (QAI) or its tertiary variety. 4 It has been shown that pholcodine induces the production of IgE antibodies to QAI-sensitising properties, therefore being an alternative source of sensitisation to NMBAs. WebDec 3, 2015 · Water Solubility: 0.454 mg/mL: ALOGPS: logP: 3.77: ALOGPS: logP: 4.1: Chemaxon: logS-2.6: ALOGPS: pKa (Strongest Acidic) 9.55: Chemaxon: pKa (Strongest …
WebAccording to Chabrier [ (15)] , pholcodine appears in the form of colourless micro-crystals, with a melting point varying between +90° and 91°.It is odourless, with a slightly bitter … http://www.chemyq.com/En/xz/xz12/118587ibcko.htm
WebJul 15, 2024 · Solubility : 20 mg/mL. Partition coefficient n-octanol/water : no data available. Vapour pressure : no data available. Density and/or relative density : 1.34g/cm3. Relative …
WebMay 26, 2016 · If the OP doesn't mind I'd like to add the findings to the OP and put it in the directory. - Fentanyl seems to be soluble at 200mg/L or 200mc/mL, though in citrate form it's soluble at 25mg/mL -source. - Nalbuphine (HCL) 35.5mg/mL -source. - Desomorphine (freebase) 1425 mg/L at 25 degrees C -source. diabetic friendly ice cream nycWebPholcodine. Pholcodine (3-morpholinoethylmorphine), a semi-synthetic alkaloid, is an MOR agonist with similar anti tussive properties to codeine (196R). It is metabolized to … cindy this is a skeletonPholcodine is an opioid cough suppressant (antitussive). It helps suppress unproductive coughs and also has a mild sedative effect, but has little or no analgesic effects. It is also known as morpholinylethylmorphine and homocodeine. Pholcodine is found in certain cough lozenges, and more commonly as an oral … diabetic friendly jellyWebExercise 2.12: Vitamins can be classified as water-soluble or fat-soluble (consider fat to be a very non-polar, hydrophobic 'solvent'. Decide on a classification for each of the vitamins shown below. Exercise 2.13: Both aniline and phenol are insoluble in pure water. Predict the solubility of these two compounds in 10% aqueous hydrochloric acid ... diabetic friendly juiceWebPromethazine + Pholcodine is a combination of two medicines: Promethazine and Pholcodine, which relieves dry cough. Promethazine is an antiallergic. It blocks the action of a chemical messenger (histamine) which is responsible to trigger cough due to allergy. Pholcodine is a cough suppressant. diabetic friendly japanese foodWebDec 1, 2011 · Pholcodine and its five structural analogues such as morphine, codeine, thebaine, oripavine, and papaverine were separated in less than 10 minutes using … diabetic friendly k cupsWebSubstance name : Pholcodine Product code : 201600714 Synonyms : Pholcodine, salts, hydrates, isomers and impurities where applicable Other means of identification : Ph.Eur. … cindy thomas archer