Cholesteryl pullulan

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August undefined, 2024

WebPullulan is a commercially exploited biodegradable extracellular polysaccharide used in coatings and wrappings potential and as a food ingredient. Also the polysaccharide β-glucan produced by Aureobasidium is commercially available. It is identified as an effective substance to improve animal health condition. WebSummary. Cholestyramine (Questran, Questran Light) is a medication prescribed to reduce cholesterol level in the blood, relieve itching of liver disease, and to treat overdoses of …

Synthesis and characterization of biotin modified …

WebDec 25, 2024 · Pullulan has been progressively defined as base-producing material of gene and drug nanocarriers. The most popular feature of these nanocarriers is the utilization of hydrophobic derivatives of pullulan, like cholesteryl-pullulan since this produces an amphiphilic pullulan derivative with the ability to form nanoparticles by self-aggregation. WebCholesteryl pullulan (CHP) is a novel antigen delivery system for cancer vaccines. This study evaluated the safety, immune responses and clinical outcomes of patients who received a CHP-MAGE-A4 ... cnur 833 organizational context of practice

Pullulan and pullulan derivatives as promising biomolecules for …

WebEnter the email address you signed up with and we'll email you a reset link. WebApr 16, 2024 · Complexes of cholesteryl pullulan (CHP) nanoparticles that contain a tumor antigen are a new type of cancer vaccine that consists of a novel antigen delivery system that presents multiple epitope peptides to both the major histocompatibility complex (MHC) class I and class II pathways [ 9 ]. Web暨南大学,数字图书馆. 开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 calculated colouring maths

Selective and Effective Cytotoxicity of Folic Acidconjugated ...

Safety Study of a Recombinant Protein Vaccine to Treat Esophageal ...

WebOct 29, 2009 · However, there are no standard therapies established for recurrent esophageal cancer. NY-ESO-1 antigen is expressed in 33% of patients. NY-ESO-1 protein is applicable without limitation by HLA types, and injected as a complex with cholesteryl pullulan (CHP), forming nano-particles (IMF-001), it can activate both CD4+ and CD8+ … WebNov 1, 2006 · We previously reported that cholesteryl pullulan (CHP) deriva-tives were effective carriers drug delivery systems in targeting cancer cells. We have now synthesized folic acid-conjugated CHP... cnu president\\u0027s leadership program calculated colouring sheets

"WebJan 2, 2014 · Synthesis of cholesteryl pullulan (CHSP) conjugates The cholesteryl pullulan, with an average degree of substitution of 5.4 per 100 glucose units, was … " - Cholesteryl pullulan

Cholesteryl pullulan

Dose-dependent effects of NY-ESO-1 protein vaccine …

WebDec 6, 2012 · Self-assembled protein-loaded pH-sensitive cholesteryl pullulan-based nanogels were developed to retain the encapsulated protein at the physiological … WebJan 1, 2014 · Intracellular delivery of exogenous proteins is a field of bioscience that has grown rapidly in recent years, driven by the potential clinical applications. We developed a protein nanocarrier composed of amphiphilic polysaccharide nanogels formed by self-assembly of ethylenediamine- and cholesteryl group-bearing pullulan (CHP-NH 2). The …

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WebAug 3, 2024 · To harness the benefits of mucosal vaccines, various mucosal antigen delivery vehicles are under development, and a cationic cholesteryl-group-bearing pullulan nanogel (cCHP nanogel) has emerged ... WebNov 1, 2006 · We previously reported that cholesteryl pullulan (CHP) deriva-tives were effective carriers drug delivery systems in targeting cancer cells. We have now …

WebThe CHP-HER2 vaccine, comprising truncated 146HER2 protein complexed with nanogels of cholesteryl pullulan (CHP), is a novel protein antigen vaccine that elicits 146HER2-specific CD8 (+) and CD4 (+) T-cell immune responses in … WebMar 22, 2024 · We have been developing the cholesteryl pullulan (CHP)-antigen protein nanoparticle as a cancer vaccine for esophageal cancer [ 13, 14 ]. A CHP nanoparticle that contains a tumor antigen is a new type of cancer vaccine with a novel antigen delivery system for both the MHC class I and class II pathways.

WebJan 8, 2024 · Fujioka-Kobayashi et al. studied the combination of FGF-18 with the bone morphogenic protein (BMP)-2 and found it was sufficient at showing significant bone regeneration potential in crosslinked acrylol cholestrol modified pullulan nanogels. These factors were combined with stimulated thick trabecular bone formation . Charoenlarp et … WebExpert opinion: The most advanced models of nanogel-based vaccines comprise candidates against cancer, based on cholesteryl pullulan nanogels evaluated in clinical trials with promising findings; as well as some vaccines against respiratory pathogens tested in …

WebAbstract. In this study, a novel nanoparticulate drug delivery platform with inherent targeting ability to hepatic carcinoma cells and reduction-triggered drug release …

WebHere, we synthesized cholesteryl-modified aminated pullulan polymers (CHPNs) with different amounts of cholesterol succinate (CHS). We characterized the three hydrophobically modified polymers (CHPN 1, … cnu registrar\u0027s officeWebApr 11, 2024 · The obtained cholesteryl-hyaluronic acid-drug compounds were rapidly shaped into compressed NG with a size of 50 nm with the help of ultrasonication [60]. The method of developing hydrophobic cholesterol-altered amino-pullulan (CHAP) compounds from pullulan that has been grafted with hydrophobic groups and ethylenediamine is … calculated colouring pdfWebCholesteryl Hexyl Dicarbamate Pullulan is Pullulan (q.v.) modified with cholesterylhexamethylenediisocyanate side chains. Common concerns See how this … cnu registrar\\u0027s office